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In fact, San Francisco-based Juul Labs, which commands 75% of the e-cig market, says in its mission statement that the company aims to eliminate cigarettes by giving adult smokers "the tools to reduce or eliminate their consumption entirely." In an emailed statement, Juul didn't directly address the decision by some of its users to revert to cigarettes, but again clung to the refrain that its products are "designed to help adult smokers switch from combustible cigarettes to an alternative nicotine delivery system." Ted Kwong, a Juul spokesman, said Juul is not designed to get people off nicotine or to treat nicotine dependence

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The odds ratio (OR) for graft failure in smokers was found to be approximately 2.5 times higher than that of non-smokers

This article first appeared in The Hollywood Reporters January awards special issue